{"id":530,"date":"2020-06-23T11:55:53","date_gmt":"2020-06-23T09:55:53","guid":{"rendered":"https:\/\/embolog.serumwerk.de\/?page_id=530"},"modified":"2024-11-15T11:57:26","modified_gmt":"2024-11-15T10:57:26","slug":"administration","status":"publish","type":"page","link":"https:\/\/embolog.serumwerk.de\/en\/administration\/","title":{"rendered":"Administration"},"content":{"rendered":"

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EmboLog\u00ae<\/sup> S<\/h1>\n

Dosage \/ Administration<\/h1>\n

” content_phone=”<\/p>\n

EmboLog\u00ae<\/sup> S<\/h1>\n

Dosage \/ Administration<\/h1>\n

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EmboLog\u00ae<\/sup> S – Dosage \/ Administration<\/h1>\n

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EmboLog\u00ae<\/sup>\u00a0S<\/span> is intended for embolization of blood vessels, especially for the local application in minimal invasive treatment, such as intra-arterial occlusion in liver tumour therapy. The embolization effect of EmboLog\u00ae<\/sup>\u00a0S<\/span> leads to a short-term vascular occlusion of blood vessels and reduced blood flow.<\/p>\n

When cytostatic drugs are administered prior to the intended embolization, the effect of EmboLog\u00ae<\/sup>\u00a0S<\/span> leads to an increased duration of exposure of the cytostatic drug at the target area.<\/p>\n

Depending on the size and vascularisation of the tumour, the arterial blood flow and the arteriovenous shunt volume, EmboLog\u00ae<\/sup>\u00a0S<\/span> can be given at a dosage of between 2.5 and 7.5 ml (150 – 450 mg). A maximum dose of 15 ml\/900 mg is possible in special cases. Local chemotherapy can be carried out in several cycles lasting several days at intervals of 2 – 6 weeks. It is advisable to perform a check angiography at about 5 to 10 minute intervals to rule out any back-flow.<\/p>\n

When EmboLog\u00ae<\/sup>\u00a0S<\/span> is used, a desirable, optimal slowing of blood flow in the tumour-bearing organ \/ organ segment can be recorded individually by angiographic monitoring. To do this, the tip of the catheter used should be positioned selectively in the vicinity of the tumour via the artery of the target organ.<\/p>\n

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EmboLog\u00ae S – Dosage \/ AdministrationEmboLog\u00ae\u00a0S is intended for embolization of blood vessels, especially for the local application in minimal invasive treatment, such as intra-arterial occlusion in liver tumour therapy. The embolization effect of EmboLog\u00ae\u00a0S leads to a short-term vascular occlusion of blood vessels and reduced blood flow. When cytostatic drugs are administered prior to […]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"[et_pb_section fb_built=\"1\" _builder_version=\"4.4.8\" custom_padding=\"17px||36px|||\" global_module=\"126\" saved_tabs=\"all\"][et_pb_row _builder_version=\"4.4.8\" width=\"90%\" max_width=\"1600px\"][et_pb_column type=\"4_4\" _builder_version=\"4.4.8\"][et_pb_image src=\"https:\/\/embolog.serumwerk.de\/wp-content\/uploads\/2020\/06\/Header-2-scaled.jpg\" title_text=\"Header 2\" _builder_version=\"4.4.8\" z_index=\"-112\"][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\"1\" module_class=\"diagonal-shadow\" _builder_version=\"4.4.8\" custom_padding=\"0px||0px|||\" bottom_divider_color=\"#067ec7\"][et_pb_row _builder_version=\"4.4.8\"][et_pb_column type=\"4_4\" _builder_version=\"4.4.8\"][et_pb_text _builder_version=\"4.4.8\" header_font=\"Open Sans|700|||||||\" header_text_align=\"center\" header_text_color=\"#067ec7\"]

EmboLog\u00ae<\/sup> S - Dosierung \/ Anwendung<\/h1>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" use_custom_gutter=\"on\" make_equal=\"on\" disabled_on=\"on|off|off\" _builder_version=\"4.4.8\" max_width=\"1000px\" custom_padding=\"||3px|||\"][et_pb_column type=\"1_2\" _builder_version=\"4.4.8\" background_image=\"https:\/\/embolog.serumwerk.de\/wp-content\/uploads\/2020\/06\/transparenterK\u00f6rpermitLebertumor.jpg\" background_size=\"initial\" custom_padding=\"150px||150px||true|false\" background_last_edited=\"on|phone\"][et_pb_button button_text=\"?\" module_class=\"divimegapro-393\t\" _builder_version=\"4.4.8\" custom_button=\"on\" button_text_color=\"#ffffff\" button_bg_color=\"#000000\" button_border_width=\"0px\" button_border_radius=\"100px\" button_use_icon=\"off\" transform_translate=\"59%|296%\" transform_translate_linked=\"off\" custom_margin=\"||||false|false\" custom_padding=\"0px|11px|0px|11px|true|true\"][\/et_pb_button][et_pb_button button_text=\"?\" module_class=\"divimegapro-401\t\" _builder_version=\"4.4.8\" custom_button=\"on\" button_text_color=\"#ffffff\" button_bg_color=\"#000000\" button_border_width=\"0px\" button_border_radius=\"100px\" button_use_icon=\"off\" transform_translate=\"16%|711%\" transform_translate_linked=\"off\" custom_margin=\"||||false|false\" custom_padding=\"0px|11px|0px|11px|true|true\"][\/et_pb_button][\/et_pb_column][et_pb_column type=\"1_2\" _builder_version=\"4.4.8\"][et_pb_text _builder_version=\"4.4.8\" text_font=\"|300|||||||\" text_orientation=\"justified\"]

EmboLog\u00ae<\/sup> S Injektionssuspension ist ein Adjuvans bei der intraarteriellen Therapie von inoperablen Lebertumoren und Lungentumoren in Kombination mit Zytostatika, welches die Optimierung der intratumoralen Wirkstoffanreicherung zum Ziel hat.
In Abh\u00e4ngigkeit von der Gr\u00f6\u00dfe und der Vaskularisierung des Tumors, dem arteriellen Blutfluss und dem arterioven\u00f6sen Shuntvolumen kann EmboLog\u00ae<\/sup> S in einer Dosierung zwischen 2,5 und 7,5 ml (150-450\u00a0mg) gegeben werden. In Einzelf\u00e4llen ist eine maximale Dosis von 15 ml\/900 mg m\u00f6glich. Eine lokale Chemotherapie kann \u00fcber mehrere Zyklen im Abstand von 2 \u2013 6\u00a0Wochen durchgef\u00fchrt werden.
Eine unter Verwendung von EmboLog\u00ae<\/sup> S erw\u00fcnschte optimale Blutflussverlangsamung im tumortragenden Organ\/Organsegment kann individuell unter angiographischer Kontrolle ermittelt werden. Dazu wird die Spitze des verwendeten Katheters selektiv \u00fcber die Arterie des Zielorgans in die N\u00e4he der Tumore positioniert.\r\nEmboLog\u00ae<\/sup> S sollte mit der fertigen Wirkstoffl\u00f6sung auf ca. das doppelte Volumen (10 \u2013 30 ml) verd\u00fcnnt werden, so dass sich eine Konzentration der St\u00e4rkemikrosph\u00e4ren von ca. 15 \u2013 30\u00a0mg\/ml ergibt. Das EmboLog\u00ae<\/sup> S - Zytostatika \u2013 Gemisch sollte \u00fcber einen Zeitraum von ca. 20 bis 30 Minuten appliziert werden. Es wird empfohlen, in Abst\u00e4nden von ca. 5 \u2013 10 Minuten eine Kontrollangiographie zum Ausschluss eines R\u00fcckflusses des therapeutischen Gemisches durchzuf\u00fchren.<\/span><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=\"off|on|on\" _builder_version=\"4.4.8\"][et_pb_column type=\"4_4\" _builder_version=\"4.4.8\"][et_pb_image src=\"https:\/\/embolog.serumwerk.de\/wp-content\/uploads\/2020\/06\/transparenterK\u00f6rpermitLebertumor.jpg\" title_text=\"transparenter K\u00f6rper mit Lebertumor\" _builder_version=\"4.4.8\"][\/et_pb_image][et_pb_button button_text=\"?\" module_class=\"divimegapro-393\t\" _builder_version=\"4.4.8\" custom_button=\"on\" button_text_color=\"#ffffff\" button_bg_color=\"#000000\" button_border_width=\"0px\" button_border_radius=\"100px\" button_use_icon=\"off\" transform_translate=\"50%|-600%\" transform_translate_linked=\"off\" custom_margin=\"||||false|false\" custom_padding=\"0px|11px|0px|11px|true|true\"][\/et_pb_button][et_pb_button button_text=\"?\" module_class=\"divimegapro-401\" _builder_version=\"4.4.8\" custom_button=\"on\" button_text_color=\"#ffffff\" button_bg_color=\"#000000\" button_border_width=\"0px\" button_border_radius=\"100px\" button_use_icon=\"off\" transform_translate=\"24%|-550%\" transform_translate_linked=\"off\" custom_margin=\"||||false|false\" custom_padding=\"0px|11px|0px|11px|true|true\"][\/et_pb_button][et_pb_text _builder_version=\"4.4.8\" text_font=\"|300|||||||\" text_orientation=\"justified\" custom_margin=\"-120px||||false|false\"]

EmboLog\u00ae<\/sup>** S Injektionssuspension ist ein Adjuvans bei der intraarteriellen Therapie von inoperablen Lebertumoren und Lungentumoren in Kombination mit Zytostatika, welches die Optimierung der intratumoralen Wirkstoffanreicherung zum Ziel hat.
In Abh\u00e4ngigkeit von der Gr\u00f6\u00dfe und der Vaskularisierung des Tumors, dem arteriellen Blutfluss und dem arterioven\u00f6sen Shuntvolumen kann EmboLog\u00ae<\/sup>** S in einer Dosierung zwischen 2,5 und 7,5 ml (150-450\u00a0mg) gegeben werden. In Einzelf\u00e4llen ist eine maximale Dosis von 15 ml\/900 mg m\u00f6glich. Eine lokale Chemotherapie kann \u00fcber mehrere Zyklen im Abstand von 2 \u2013 6\u00a0Wochen durchgef\u00fchrt werden.
Eine unter Verwendung von EmboLog\u00ae<\/sup>** S erw\u00fcnschte optimale Blutflussverlangsamung im tumortragenden Organ\/Organsegment kann individuell unter angiographischer Kontrolle ermittelt werden. Dazu wird die Spitze des verwendeten Katheters selektiv \u00fcber die Arterie des Zielorgans in die N\u00e4he der Tumore positioniert.\r\nEmboLog\u00ae<\/sup>** S sollte mit der fertigen Wirkstoffl\u00f6sung auf ca. das doppelte Volumen (10 \u2013 30 ml) verd\u00fcnnt werden, so dass sich eine Konzentration der St\u00e4rkemikrosph\u00e4ren von ca. 15 \u2013 30\u00a0mg\/ml ergibt. Das EmboLog\u00ae<\/sup>** S - Zytostatika \u2013 Gemisch sollte \u00fcber einen Zeitraum von ca. 20 bis 30 Minuten appliziert werden. Es wird empfohlen, in Abst\u00e4nden von ca. 5 \u2013 10 Minuten eine Kontrollangiographie zum Ausschluss eines R\u00fcckflusses des therapeutischen Gemisches durchzuf\u00fchren.<\/span><\/p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_2\" _builder_version=\"4.4.8\" custom_padding=\"20px||0px|||\"][et_pb_column type=\"1_2\" _builder_version=\"4.4.8\"][\/et_pb_column][et_pb_column type=\"1_2\" _builder_version=\"4.4.8\"][et_pb_button button_url=\"https:\/\/embolog.serumwerk.de\/wp-content\/uploads\/2020\/06\/GA_EmboLog-S_LeLuT_v01_RZ.pdf\" button_text=\"Gebrauchsinformation\" _builder_version=\"4.4.8\" custom_button=\"on\" button_text_color=\"#ffffff\" button_bg_color=\"#067ec7\" button_border_width=\"0px\"][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]","_et_gb_content_width":""},"_links":{"self":[{"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/pages\/530"}],"collection":[{"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/comments?post=530"}],"version-history":[{"count":49,"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/pages\/530\/revisions"}],"predecessor-version":[{"id":1503,"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/pages\/530\/revisions\/1503"}],"wp:attachment":[{"href":"https:\/\/embolog.serumwerk.de\/en\/wp-json\/wp\/v2\/media?parent=530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}